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MiniKros Plus offer the same gentle and efficient tangential flow filtration of MiniKros modules,
plus the option of 3 different inlet/outlet connection types (1-1/2" Sanitary, 3/4" Sanitary and 1/2" Hose Barb)
for increased convenience and flexibility. Perfectly suited for process optimization of 300 mL
to 100 liters and scaling filtration applications up to production volumes, the MiniKros Plus module
consists of Spectrum's high quality hollow fibers potted in a symmetric housing with two filtrate side ports.
The hollow fiber membrane geometry and flow dynamics provide consistent filtration performance, direct scalability
for production and high product recovery essential for pharmaceutical and diagnostic process development.
All modules are autoclavable or are available irradiated (irr).
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Dimensions:  |
| SA (cm2) | Scale
Length | ID (mm) | TL (cm) | L (cm) | EL (cm) |
| 600 - 1050 | 1xFL | 18.8 | 28.6 | 23.5 | 20.6 |
| 1800 - 3800 | 1xFL | 31.2 | 28.6 | 23.5 | 20.6 |
| 3800 - 6600 | 2xFL | 31.2 | 48.1 | 47.2 | 44.0 |
| 5700 - 9900 | 3xFL | 31.2 | 73.8 | 69.0 | 65.8 |
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| Housing: | Clear and Pigmented Polysulfone |
| Inlet/Outlet Ports: | 1-1/2" Sanitary, 3/4" Sanitary, 1/2" Hose Barb, 3/8" Hose Barb |
| Filtrate Ports: | 3/8" Hose Barb |
| Potting: | Polyurethane |
| Process Volume: | 300 mL - 100 L |
| Surface Area: | 600 - 9900 cm2 |
| Membrane | Fiber ID | MWCO |
| Mixed Cellulose Ester (ME) | 0.6 mm | 0.2 µm, 0.1 µm |
| Polyethersulfone (PES) | 0.5 mm | 0.5 µm, 0.2 µm |
| Polysulfone (PS) | 0.5 mm, 1.0 mm | 0.05 µm, 20 nm (500 kD), 100 kD, 50 kD, 10 kD |
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Advantages of Disposability
- Easier FDA Validation
- Saves Money & Time
- No Cross-Contamination
- Less Down-Time
- Low Shear
- Directly Scalable for Production
- Easy Retrofit for other HF Modules
Applications:
- Cell Concentration, Clarification and Diafiltration
- Lysate Clarification
- VLP and Virus Concentration and Diafiltration
- VLP and Virus Clarification
- Protein Purification, Concentration and Diafiltration
- Nucleic Acid Diafiltration and Concentration
- NanoParticle and Latex Particle Diafiltration and Fractionation
- In situ Conjugation and Fractionation
- Bacteria Concentration and Diafiltration
- Liposome, siRNA Concentration and Diafiltration
- Inclusion body Clarification and Concentration
- Bioreactor cell Perfusion and Media Exchange
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RELATED PRODUCTS:
MiniKros Plus System
for volumes from 300 ml to 100 liters
Learn More >
MiniKros Pilot System
for volumes 10 to 1000 liters
Learn More >
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