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The MiniKros modules are perfectly suited for process optimization and scaling filtration applications
up to the production volumes. Spectrum combines the gentle and highly efficient tangential flow filtration
with hollow fiber membrane geometry to make process scale up quick and simple. The MiniKros module consists
of Spectrum high quality hollow fibers potted in a symmetric housing with circulation inlet/outlet ports and
two filtrate side ports. The hollow fiber membrane geometry and flow dynamics provide consistent filtration
performance, direct scalability for production and high product recovery essential for pharmaceutical and
diagnostic process development. All modules are autoclavable or are available irradiated (irr).
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Dimensions:  |
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| SA (cm2) | Scale Length | ID (mm) | TL (cm) | L (cm) | EL (cm) |
| 250-1050 | 1xFL | 18.8 | 27.6 | 22.3 | 20.8 |
| 1500-3100 | 1xFL | 31.2 | 27.6 | 22.3 | 20.8 |
| 3200-6600 | 2xFL | 31.2 | 51.0 | 46.0 | 44.1 |
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| Housing: | Clear and pigmented Polysulfone |
| Connections: | 1/2 inch hose barb inlet/outlet ports
Female Luer Lok filtrate (FLL) |
| Potting: | Polyurethane |
| Process Volume: | 300 mL to 100 Liters |
| Surface Area: | 5 to 6,600 cm2 |
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| Membrane | Fiber ID | MWCO |
| Mixed Cellulose Ester (ME) | 0.6 mm, 1.0 mm | 0.2 µm, 0.1 µm |
| Polyethersulfone (PES) | 0.5 mm, 1.0 mm | 0.5 µm, 0.2 µm |
| Polysulfone (PS) | 0.5 mm, 1.0 mm | 0.05 µm, 20 nm (500 kD), 100 kD, 50 kD, 10 kD |
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Advantages of Disposability
- Easier FDA Validation
- Saves Money & Time
- No Cross-Contamination
- Less Down-Time
- Low Shear
- Directly Scalable for Production
- Easy Retrofit for other HF Modules
Applications:
- Cell Concentration, Clarification and Diafiltration
- Lysate Clarification
- VLP and Virus Concentration and Diafiltration
- VLP and Virus Clarification
- Protein Purification, Concentration and Diafiltration
- Nucleic Acid Diafiltration and Concentration
- NanoParticle and Latex Particle Diafiltration and Fractionation
- In situ Conjugation and Fractionation
- Bacteria Concentration and Diafiltration
- Liposome, siRNA Concentration and Diafiltration
- Inclusion body Clarification and Concentration
- Bioreactor cell Perfusion and Media Exchange
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RELATED PRODUCTS:
MiniKros Plus System
for volumes from 300 ml to 100 liters
Learn More >
MiniKros Pilot System
for volumes 10 to 1000 liters
Learn More >
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