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Hollow Fiber Cell and Tissue Culturing maximizes surface area to minimize the volume of culture medium required.
The porous hollow fibers form a 3 dimensional network of capillaries that continually delivers a supply of fresh
media and nutrients to the cultured cells that remain isolated in the Extra-Capillary Space (ECS).
The fiber membrane provides a selectively permeable barrier that permits passage of metabolic by-products
(lactic acid & CO2) away from the cells while culture-dependent nutrients (glucose, serum & 02)
permeate into the culture.
This efficient exchange results in increased cell densities and higher yields of secreted product.
The porous membrane also retains important growth factors allowing the reduction or
possibly elimination of serum. Cultures remain active up to six months, maintaining better viability and
morphology with increased production, enhanced quality, and improved expression of protein products.
CellMax Duo Hollow Fiber Bioreactor System for 2 cultures
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CellMax Quad Hollow Fiber Bioreactor System for 4 cultures
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CellMax High Flow Quad for 4 cultures
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